Invention Grant
- Patent Title: Systems and methods for determining a weighted mean intensity
- Patent Title (中): 用于确定加权平均强度的系统和方法
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Application No.: US10287130Application Date: 2002-11-04
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Publication No.: US07966130B2Publication Date: 2011-06-21
- Inventor: Roland Stoughton , Hongyue Dai
- Applicant: Roland Stoughton , Hongyue Dai
- Applicant Address: US WA Redmond
- Assignee: Microsoft Corporation
- Current Assignee: Microsoft Corporation
- Current Assignee Address: US WA Redmond
- Agency: Klarquist Sparkman LLP
- Main IPC: G06F19/00
- IPC: G06F19/00 ; G06F7/38 ; G01N33/48

Abstract:
A method for fluorophore bias removal in microarray experiments in which the fluorophores used in microarray experiment pairs are reversed. Further, a method for calculating the individual errors associated with each measurement made in nominally repeated microarray experiments. This error measurement is optionally coupled with rank based methods in order to determine a probability that a cellular constituent is up or down regulated in response to a perturbation. Finally, a method for determining the confidence in the weighted average of the expression level of a cellular constituent in nominally repeated microarray experiments.
Public/Granted literature
- US20030093227A1 Statistical combining of cell expression profiles Public/Granted day:2003-05-15
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