Systems and methods for an audio-based content management, navigation and retrieval system are provided. The system translates and organizes content, for example text, Podcasts, RSS, pictures, video, into audio output, and provides intelligent access to the content for use on the internet, mobile phones, MP3 devices, or other digital devices. A user may listen to and navigate content by listening to streaming audio and performing simple keystroke or audio commands from an Internet enabled or other digital device.