Invention Grant
- Patent Title: Promiscuous HER-2/Neu CD4 T cell epitopes
- Patent Title (中): 混杂的HER-2 / Neu CD4 T细胞表位
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Application No.: US11836645Application Date: 2007-08-09
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Publication No.: US07972602B2Publication Date: 2011-07-05
- Inventor: Jami B. Wollan , Lori A. Jones
- Applicant: Jami B. Wollan , Lori A. Jones
- Applicant Address: US WA Seattle
- Assignee: Dendreon Corporation
- Current Assignee: Dendreon Corporation
- Current Assignee Address: US WA Seattle
- Agency: Kilpatrick Townsend & Stockton LLP.
- Main IPC: A61K39/00
- IPC: A61K39/00
Abstract:
The present invention relates to the discovery of novel T cell epitopes of the human HER-2/Neu protein that is promiscuous for at least 25 different HLA-DR alleles. The invention also relates to compositions that contain one of the novel epitopes or a fusion peptide of such a epitope and a heterologous polypeptide. Further disclosed herein is the use of the epitopes or their fusion peptides, and compositions containing the epitopes or their fusion peptides.
Public/Granted literature
- US20080107667A1 PROMISCUOUS HER-2/NEU CD4 T CELL EPITOPES Public/Granted day:2008-05-08
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