Invention Grant
US07972767B2 Method for culturing mesenchymal stem cell and method for producing biological tissue prosthesis 有权
培养间充质干细胞的方法和生物组织假体的制备方法

  • Patent Title: Method for culturing mesenchymal stem cell and method for producing biological tissue prosthesis
  • Patent Title (中): 培养间充质干细胞的方法和生物组织假体的制备方法
  • Application No.: US11919303
    Application Date: 2006-05-09
  • Publication No.: US07972767B2
    Publication Date: 2011-07-05
  • Inventor: Konghua Lin
  • Applicant: Konghua Lin
  • Applicant Address: JP Tokyo
  • Assignee: Olympus Corporation
  • Current Assignee: Olympus Corporation
  • Current Assignee Address: JP Tokyo
  • Agency: Scully, Scott, Murphy & Presser, P.C.
  • Priority: JP2005-135780 20050509; JP2005-217835 20050727
  • International Application: PCT/JP2006/309320 WO 20060509
  • International Announcement: WO2006/121043 WO 20061116
  • Main IPC: A01N1/02
  • IPC: A01N1/02 A01N1/00 C12N5/02
Method for culturing mesenchymal stem cell and method for producing biological tissue prosthesis
Abstract:
The purpose is to proliferate a mesenchymal stem cell to a sufficient degree while reducing the amount of blood serum contained in a biological tissue progenitor cell to be grafted, and to efficiently differentiate the mesenchymal stem cell into the biological tissue progenitor cell. There is provided a method for culturing a mesenchymal stem cell, comprising: a first culture step of proliferating a mesenchymal stem cell in a medium containing blood serum; and a second culture step of differentiating the mesenchymal stem cell into a biological tissue progenitor cell in a medium containing blood serum at a lower concentration than that in the medium used in the first culture step.
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