Invention Grant
- Patent Title: Method for culturing mesenchymal stem cell and method for producing biological tissue prosthesis
- Patent Title (中): 培养间充质干细胞的方法和生物组织假体的制备方法
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Application No.: US11919303Application Date: 2006-05-09
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Publication No.: US07972767B2Publication Date: 2011-07-05
- Inventor: Konghua Lin
- Applicant: Konghua Lin
- Applicant Address: JP Tokyo
- Assignee: Olympus Corporation
- Current Assignee: Olympus Corporation
- Current Assignee Address: JP Tokyo
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: JP2005-135780 20050509; JP2005-217835 20050727
- International Application: PCT/JP2006/309320 WO 20060509
- International Announcement: WO2006/121043 WO 20061116
- Main IPC: A01N1/02
- IPC: A01N1/02 ; A01N1/00 ; C12N5/02

Abstract:
The purpose is to proliferate a mesenchymal stem cell to a sufficient degree while reducing the amount of blood serum contained in a biological tissue progenitor cell to be grafted, and to efficiently differentiate the mesenchymal stem cell into the biological tissue progenitor cell. There is provided a method for culturing a mesenchymal stem cell, comprising: a first culture step of proliferating a mesenchymal stem cell in a medium containing blood serum; and a second culture step of differentiating the mesenchymal stem cell into a biological tissue progenitor cell in a medium containing blood serum at a lower concentration than that in the medium used in the first culture step.
Public/Granted literature
- US20100028997A1 Method for culturing mesenchymal stem cell and method for producing biological tissue prosthesis Public/Granted day:2010-02-04
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