Invention Grant
- Patent Title: Skin aging marker and technique for use thereof
- Patent Title (中): 皮肤老化标记及其使用技术
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Application No.: US12064602Application Date: 2006-08-22
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Publication No.: US07972788B2Publication Date: 2011-07-05
- Inventor: Satoshi Miyata , Kaoru Miyazaki , Chie Yasuda , Akihiro Iwamatsu
- Applicant: Satoshi Miyata , Kaoru Miyazaki , Chie Yasuda , Akihiro Iwamatsu
- Applicant Address: JP Yokohama-shi JP Yokohama-shi JP Yokohama-shi JP Tokyo
- Assignee: Fancl Corporation,Yokohama City University,Kihara Memorial Yokohama Foundation for the Advancement of Life Sciences,Kirin Holdings Kabushiki Kaisha
- Current Assignee: Fancl Corporation,Yokohama City University,Kihara Memorial Yokohama Foundation for the Advancement of Life Sciences,Kirin Holdings Kabushiki Kaisha
- Current Assignee Address: JP Yokohama-shi JP Yokohama-shi JP Yokohama-shi JP Tokyo
- Agency: Knobbe Martens Olson & Bear LLP
- Priority: JP2005-240820 20050823
- International Application: PCT/JP2006/316407 WO 20060822
- International Announcement: WO2007/023808 WO 20070301
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/53 ; C07K1/00 ; C07K14/00 ; C07K17/00 ; A61K38/17 ; C08H1/06
Abstract:
It is an object of the present invention to find substances that can be used as skin aging markers, and the present invention provides a method for determining the degree of skin aging, including measurement of expression of secretory proteins and/or intracellular proteins and/or their genes in skin cells and/or skin tissues, wherein the secretory proteins and/or intracellular proteins change their expression with aging of skin. The present invention also provides a kit for determining the degree of skin aging and a method for identifying substances effective in the prevention of skin aging.
Public/Granted literature
- US20090305242A1 SKIN AGING MARKER AND TECHNIQUE FOR USE THEREOF Public/Granted day:2009-12-10
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