Invention Grant
US07972795B2 Angiopoietin-like 2 as a biomarker of vascular endothelial cell abnormal function and senescence
有权
促血管生成素2作为血管内皮细胞异常功能和衰老的生物标志物
- Patent Title: Angiopoietin-like 2 as a biomarker of vascular endothelial cell abnormal function and senescence
- Patent Title (中): 促血管生成素2作为血管内皮细胞异常功能和衰老的生物标志物
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Application No.: US11812621Application Date: 2007-06-20
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Publication No.: US07972795B2Publication Date: 2011-07-05
- Inventor: Eric Thorin , Nada Farhat , Nathalie Trescases
- Applicant: Eric Thorin , Nada Farhat , Nathalie Trescases
- Applicant Address: CA Montreal, Quebec
- Assignee: Institut de Cardiologie de Montreal
- Current Assignee: Institut de Cardiologie de Montreal
- Current Assignee Address: CA Montreal, Quebec
- Agency: Holland & Hart, LLP
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
A method for assessing a physiological state of a mammal. The method includes: obtaining from the mammal a biological sample; measuring the expression of angiopoietin-like 2 in the biological sample; and assessing the physiological state of the mammal by comparing the measured expression of the angiopoietin-like 2 to a predetermined normal expression level in normal subjects, wherein an increase in angiopoietin-like 2 level over the predetermined normal expression level indicates an abnormal physiological state.
Public/Granted literature
- US20080166717A1 Angiopoietin-like 2 as a biomarker of vascular endothelial cell abnormal function and senescence Public/Granted day:2008-07-10
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