Invention Grant
- Patent Title: Chromatography detection apparatus, detection method, and kit utilizing the same
- Patent Title (中): 色谱检测装置,检测方法和使用其的试剂盒
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Application No.: US11628621Application Date: 2005-06-07
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Publication No.: US07972872B2Publication Date: 2011-07-05
- Inventor: Ryo Shida , Hiromi Ito
- Applicant: Ryo Shida , Hiromi Ito
- Applicant Address: JP Tokyo
- Assignee: Denka Seiken Co., Ltd.
- Current Assignee: Denka Seiken Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Foley & Lardner LLP
- Agent Stephen A. Bent
- Priority: JP2004-169200 20040607
- International Application: PCT/JP2005/010386 WO 20050607
- International Announcement: WO2005/121794 WO 20051222
- Main IPC: G01N33/53
- IPC: G01N33/53

Abstract:
This invention provides an immunochromatography detection apparatus exhibiting excellent convenience, sensitivity, and specificity, a detection method therefore, a kit using the same, and a method for producing such apparatus and kit, by constructing a solid-phase support, on which the conditions for the reaction wherein an analyte specifically binds to a labeled reagent containing a ligand that specifically binds to the analyte and those for the reaction wherein a capture reagent specifically binds to a complex of the analyte and the labeled reagent in the immunochromatography detection method are continuously optimized, and the pretreated specimens are optimized for such reactions. This chromatography detection apparatus comprises: a sheet-like solid-phase support; a specimen-supply site thereon at which a specimen deduced to contain at least an analyte or a mixture of such specimen and a labeled reagent containing a ligand that specifically binds to the analyte is supplied; and a capture reagent site to which a capture reagent capable of specifically binding to and capturing a complex of the analyte and the labeled reagent has been immobilized, wherein at least one functional site having a particular or multiple functions is provided between the specimen-supply site and the capture reagent site.
Public/Granted literature
- US20080194013A1 Chromatography Detection Apparatus, Detection Method, and Kit Utilizing the Same Public/Granted day:2008-08-14
Information query
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