Invention Grant
- Patent Title: Identification of protein binding sites
- Patent Title (中): 鉴定蛋白质结合位点
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Application No.: US10411869Application Date: 2003-04-10
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Publication No.: US07972993B2Publication Date: 2011-07-05
- Inventor: Jelle Wouter Slootstra , Wouter Cornelis Puijk , Robbert Hans Meloen , Pieter van Dijken , Evert van Dijk
- Applicant: Jelle Wouter Slootstra , Wouter Cornelis Puijk , Robbert Hans Meloen , Pieter van Dijken , Evert van Dijk
- Applicant Address: NL Lelystad
- Assignee: Pepscan Systems B.V.
- Current Assignee: Pepscan Systems B.V.
- Current Assignee Address: NL Lelystad
- Agency: TraskBritt, P.C.
- Priority: EP00203518 20001011
- Main IPC: C40B50/14
- IPC: C40B50/14

Abstract:
The invention relates to the field of molecular recognition or detection of discontinuous or conformational binding sites or epitopes corresponding to a binding molecule, in particular, in relation to protein-protein, protein-nucleic acid, nucleic acid-nucleic acid or biomolecule-ligand interactions. The invention provides a synthetic molecular library allowing testing for, identification, characterization or detection of a discontinuous binding site capable of interacting with a binding molecule, the library having been provided with a plurality of test entities, each test entity comprising at least one first segment spotted next to a second segment, each segment having the capacity of being a potential single part of a discontinuous binding site.
Public/Granted literature
- US20030228605A1 Identification of protein binding sites Public/Granted day:2003-12-11
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