Invention Grant
US07973027B2 Compound with antimalarial activity and antimalarial drug containing the same as active ingredient
失效
具有抗疟活性的化合物和含有与活性成分相同的抗疟药
- Patent Title: Compound with antimalarial activity and antimalarial drug containing the same as active ingredient
- Patent Title (中): 具有抗疟活性的化合物和含有与活性成分相同的抗疟药
-
Application No.: US12224387Application Date: 2007-02-26
-
Publication No.: US07973027B2Publication Date: 2011-07-05
- Inventor: Tsunehiko Higuchi , Hirohisa Omiya , Naoki Umezawa , Hye-Sook Kim , Yusuke Wataya
- Applicant: Tsunehiko Higuchi , Hirohisa Omiya , Naoki Umezawa , Hye-Sook Kim , Yusuke Wataya
- Applicant Address: JP Nagoya-shi
- Assignee: Nagoya City University
- Current Assignee: Nagoya City University
- Current Assignee Address: JP Nagoya-shi
- Agency: Edwards Angell Palmer & Dodge LLP
- Priority: JP2006-049678 20060227
- International Application: PCT/JP2007/053537 WO 20070226
- International Announcement: WO2007/097450 WO 20070830
- Main IPC: A61K31/47
- IPC: A61K31/47 ; C07D215/46

Abstract:
Compounds with high antimalarial activity; and antimalarial drugs containing the same as an active ingredient. There are provided compounds with antimalarial activity represented by the chemical formula: (wherein R1 is H, Cl or OCH3; R2 is H or CH3; R3 is CH, CH2, C(CH3), CH(CH3) or C(CH3)2; Ar is imidazole, triazole, pyridine, benzene, pyrrole, furan, thiophene or derivatives thereof; n is 1 to 5; and m is 1 to 5). Further, there are provided antimalarial drugs containing these compounds with antimalarial activity or pharmacologically acceptable salts thereof as active ingredients.
Public/Granted literature
- US20090275612A1 Compound With Antimalarial Activity And Antimalarial Drug Containing The Same As Active Ingredient Public/Granted day:2009-11-05
Information query