Invention Grant
- Patent Title: Benzothiazepine and benzothiepine compounds
- Patent Title (中): 苯并硫氮杂和苯并噻吩类化合物
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Application No.: US10590458Application Date: 2005-02-25
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Publication No.: US07973030B2Publication Date: 2011-07-05
- Inventor: Takehiko Sasahara , Mitsunobu Mohri , Ken-Ichi Kasahara
- Applicant: Takehiko Sasahara , Mitsunobu Mohri , Ken-Ichi Kasahara
- Applicant Address: JP Tokyo
- Assignee: Asahi Kasei Pharma Corporation
- Current Assignee: Asahi Kasei Pharma Corporation
- Current Assignee Address: JP Tokyo
- Agency: Young & Thompson
- Priority: JP2004-128992 20040227
- International Application: PCT/JP2005/003686 WO 20050225
- International Announcement: WO2005/082874 WO 20050909
- Main IPC: A61P1/16
- IPC: A61P1/16 ; A61P3/04 ; A61P3/06 ; A61P9/10 ; A61K31/22 ; A61K31/366 ; A61K31/38 ; A61K31/381 ; A61K31/395 ; A61K31/4025 ; A61K31/428 ; A61K31/439 ; A61K31/4995 ; A61K31/5375 ; A61K31/541 ; A61K31/554 ; C07D281/10 ; C07D337/08 ; C07D409/12 ; C07D453/02 ; C07D471/08 ; C07D487/08
Abstract:
A pharmaceutical useful as a therapeutic agent and a preventive agent for hyperlipemia, and a pharmaceutical useful as a therapeutic agent and a preventive agent for hepatic disorders associated with cholestasis, particularly, primary biliary cirrhosis and primary sclerosing cholangitis, and a pharmaceutical useful as a therapeutic agent and a preventive agent for obesity, fatty liver and steatohepatitis are provided. A benzothiazepine or benzothiepine compound represented by the following formula (1A) having a thioamide bond and a quaternary ammonium substitutent:
Public/Granted literature
- US20070190041A1 Novel benzothiazepine and bensothiepine compounds Public/Granted day:2007-08-16
Information query
