Invention Grant
US07973066B2 Pyrrolo[1,2-A]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents
失效
吡咯并[1,2-A]咪唑二酮有效治疗由化疗药物引起的周围神经毒性
![Pyrrolo[1,2-A]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents](/docs/US/2011-07-05/US07973066B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrrolo[1,2-A]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents
- Patent Title (中): 吡咯并[1,2-A]咪唑二酮有效治疗由化疗药物引起的周围神经毒性
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Application No.: US12312575Application Date: 2007-11-14
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Publication No.: US07973066B2Publication Date: 2011-07-05
- Inventor: Carlo Farina , Carla Ghelardini , Paola Petrillo
- Applicant: Carlo Farina , Carla Ghelardini , Paola Petrillo
- Applicant Address: CH Schlieren
- Assignee: Neurotune AG
- Current Assignee: Neurotune AG
- Current Assignee Address: CH Schlieren
- Agency: Abelman, Frayne & Schwab
- Priority: EP06124142 20061115
- International Application: PCT/EP2007/062323 WO 20071114
- International Announcement: WO2008/058988 WO 20080522
- Main IPC: A61K31/4166
- IPC: A61K31/4166 ; C07D235/00
![Pyrrolo[1,2-A]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents](/abs-image/US/2011/07/05/US07973066B2/abs.jpg.150x150.jpg)
Abstract:
The use of a compound of formula (I), is disclosed in treating and/or preventing 5 chemotherapy-induced peripheral neurotoxicity (CIPN). The invention includes pharmaceutical compositions wherein the compound of formula (I) is present in a mixture with anticancer agents. An improved anticancer treatment with reduced CIPN-related side effects is also provided.
Public/Granted literature
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