Invention Grant
- Patent Title: Optimized anti-CD30 antibodies
- Patent Title (中): 优化抗CD30抗体
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Application No.: US12089384Application Date: 2006-10-06
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Publication No.: US07973136B2Publication Date: 2011-07-05
- Inventor: Gregory Alan Lazar , John R. Desjarlais , Philip W. Hammond , David F. Carmichael , Bao-lu Chen , Seung Y. Chu , Sher Bahadur Karki , Lori Kunkel
- Applicant: Gregory Alan Lazar , John R. Desjarlais , Philip W. Hammond , David F. Carmichael , Bao-lu Chen , Seung Y. Chu , Sher Bahadur Karki , Lori Kunkel
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Monrovia
- Agency: Dorsey & Whitney LLP
- International Application: PCT/US2006/039306 WO 20061006
- International Announcement: WO2007/044616 WO 20070419
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; A61K39/395 ; G01N33/53
Abstract:
An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcgR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.
Public/Granted literature
- US20080267976A1 Optimized Anti-Cd30 Antibodies Public/Granted day:2008-10-30
Information query
