Invention Grant
- Patent Title: Non-basic melanin concentrating hormone receptor-1 antagonists
- Patent Title (中): 非基本黑色素浓缩激素受体-1拮抗剂
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Application No.: US12907451Application Date: 2010-10-19
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Publication No.: US07973159B2Publication Date: 2011-07-05
- Inventor: William N. Washburn , Saleem Ahmad , Andres S. Hernandez
- Applicant: William N. Washburn , Saleem Ahmad , Andres S. Hernandez
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Burton Rodney; Jing G. Sun
- Main IPC: C07D495/04
- IPC: C07D495/04 ; A61K31/5025 ; A61K31/381 ; A61P3/04 ; A61P3/10 ; A61P25/22 ; A61P25/24

Abstract:
The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I. Additionally, the present application provides pharmaceutical compositions containing at least one compound according to Formula I and optionally at least one additional therapeutic agent. Finally, the present application provides methods for treating a patient suffering from an MCHR-1 modulated disease or disorder such as, for example, obesity, diabetes, depression or anxiety by administration of a therapeutically effective dose of a compound according to Formula I. where R1, R1a, R1b, A, R3, R4, R5, R5b and R6 are as defined herein.
Public/Granted literature
- US20110034375A1 NON-BASIC MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS Public/Granted day:2011-02-10
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