A method of managing information system resources to provide a message flow having a consistent level of quality of service (QoS) within and across a plurality of interconnected middleware domains is described. The method includes receiving a QoS message from a first QoS manager expressing at least one QoS requirement, translating the at least one QoS requirement to at least one parameter specific to a messaging service that communicatively couples multiple middleware domains, creating a client connection between a first middleware domain and the messaging service for receiving the message flow, transmitting the QoS message to a second middleware domain, and creating a client connection between the messaging service and the second middleware domain for transmitting the message flow.