A system includes a platform domain implementing address-indexed operations and an application domain implementing application context-oriented operations. The platform domain includes a platform interconnect to process address-indexed platform transactions and a trace monitor to generate a debug trace stream from platform transactions based on their platform context information. The application domain includes a processing component and a queue manager to queue descriptors for data frames to be processed by the application domain, each descriptor having application context information including application-specific debug information for the corresponding data frame. The processing component processes a selected data frame by accessing, from the queue manager, a descriptor associated with the selected data frame, translating an application-specific debug information of the descriptor to a corresponding platform attribute value, and providing a platform transaction to the platform interconnect for processing in the platform domain, the platform transaction having the platform attribute value in an attribute field.