Invention Grant
- Patent Title: Purification process
- Patent Title (中): 净化过程
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Application No.: US12291863Application Date: 2008-11-14
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Publication No.: US07985323B2Publication Date: 2011-07-26
- Inventor: Ulrich Beutler , Gerhard Penn
- Applicant: Ulrich Beutler , Gerhard Penn
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Karen DeBenedictis
- Priority: GB0320312.2 20030829
- Main IPC: B01D3/10
- IPC: B01D3/10 ; C07C209/84

Abstract:
Purification process for the preparation of the allylamine pharmaceutical terbinafine of formula I in free base form or acid addition salt form, by distilling crude terbinafine base, preferably by short path distillation, e.g. at a temperature above 100° C. and reduced pressure, e.g. 0.2 mbar, and recovering the purified product in free base or acid addition salt form.
Public/Granted literature
- US20090216047A1 Purification process Public/Granted day:2009-08-27
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