Invention Grant
- Patent Title: Membrane active heteropolymers
- Patent Title (中): 膜活性杂聚物
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Application No.: US12123124Application Date: 2008-05-19
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Publication No.: US07985406B2Publication Date: 2011-07-26
- Inventor: Sean D. Monahan , Darren H. Wakefield , David B. Rozema , Lori Higgs , Jon A. Wolff , James E. Hagstrom
- Applicant: Sean D. Monahan , Darren H. Wakefield , David B. Rozema , Lori Higgs , Jon A. Wolff , James E. Hagstrom
- Applicant Address: US WI Madison
- Assignee: Roche Madison Inc.
- Current Assignee: Roche Madison Inc.
- Current Assignee Address: US WI Madison
- Agent Kirk Ekena
- Main IPC: A61K31/74
- IPC: A61K31/74
Abstract:
The present invention is directed to a class of membrane active polymers useful for cellular delivery of compounds. Conjugation of the described membrane active polymers to targeting, anti-opsonization, and anti-aggregation agents provides polymers suitable for in vivo delivery. The use of multiple reversible linkages connecting component parts provides for physiologically responsive activity modulation.
Public/Granted literature
- US20090023890A1 Membrane Active Heteropolymers Public/Granted day:2009-01-22
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