Invention Grant
- Patent Title: Gastric juice-resistant device for releasing mucoadhesive active substance excipients, and method for producing this gastric juice-resistant device
- Patent Title (中): 用于释放粘膜粘附活性物质赋形剂的胃液装置及其制造方法
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Application No.: US10475785Application Date: 2002-04-22
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Publication No.: US07985427B2Publication Date: 2011-07-26
- Inventor: Despina Solomonidou , Markus Krumme , Bodo Asmussen , Joerg Kreuter
- Applicant: Despina Solomonidou , Markus Krumme , Bodo Asmussen , Joerg Kreuter
- Applicant Address: DE Andernach
- Assignee: LTS Lohmann Therapie-Systeme AG
- Current Assignee: LTS Lohmann Therapie-Systeme AG
- Current Assignee Address: DE Andernach
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: DE10120092 20010425
- International Application: PCT/EP02/04381 WO 20020422
- International Announcement: WO02/085333 WO 20021031
- Main IPC: A61K9/16
- IPC: A61K9/16 ; A61K9/20 ; A61K9/26 ; A61K9/24 ; A61K9/28 ; A61K9/34 ; A61K9/32 ; A61F13/00
Abstract:
The invention relates to a gastric juice-resistant device for releasing active substance excipients having delayed intestinal passage from a gastric juice-resistant enclosure, and which serves to increase the active substance concentration in the intestines. The inventive device is characterized in that the active substance excipient containing at least one active substance is provided in the form of a multiparticulate preparation whose individual particles have mucoadhesive properties. The invention also relates to a method for producing said device.
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