Invention Grant
- Patent Title: HIFαprolyl hydroxylation assay
- Patent Title (中): HIFα脯氨酰羟化作用
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Application No.: US11879300Application Date: 2007-07-17
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Publication No.: US07985563B2Publication Date: 2011-07-26
- Inventor: William G. Kaelin, Jr. , Mircea Ivan
- Applicant: William G. Kaelin, Jr. , Mircea Ivan
- Applicant Address: US MA Boston
- Assignee: Dana Farber Cancer Institute, Inc.
- Current Assignee: Dana Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston
- Agency: FibroGen, Inc.
- Agent Christopher M. Turner
- Main IPC: C12Q1/34
- IPC: C12Q1/34
Abstract:
The present invention provides methods of identifying compounds that decrease proline hydroxylation of the alpha subunit of hypoxia inducible factor (HIFα).
Public/Granted literature
- US20090029400A1 Pharmaceuticals and methods for treating hypoxia and screening methods therefor Public/Granted day:2009-01-29
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