Invention Grant
US07985747B2 Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions
有权
选择的CGRP拮抗剂，其制备方法及其作为药物组合物的用途
- Patent Title: Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions
- Patent Title (中): 选择的CGRP拮抗剂，其制备方法及其作为药物组合物的用途
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Application No.: US12706853Application Date: 2010-02-17
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Publication No.: US07985747B2Publication Date: 2011-07-26
- Inventor: Stephan Georg Mueller , Klaus Rudolf , Philipp Lustenberger , Dirk Stenkamp , Alexander Dreyer , Kirsten Arndt , Gerhard Schaenzle , Henri Doods , Marco Santagostino , Fabio Paleari
- Applicant: Stephan Georg Mueller , Klaus Rudolf , Philipp Lustenberger , Dirk Stenkamp , Alexander Dreyer , Kirsten Arndt , Gerhard Schaenzle , Henri Doods , Marco Santagostino , Fabio Paleari
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Alan R. Stempel
- Priority: ARP050101139 20050323; PE000336-2005/OIN 20050323; WOPCT/EP2005/003094 20050325
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D401/14 ; A61K31/551 ; A61P25/06
Abstract:
The present invention relates to the CGRP antagonists of general formula wherein A, X, D, E, G, M, Q and R1 to R3 are defined as in claim 1, the tautomers, the isomers, the diastereomers, the enantiomers, the hydrates thereof, the mixtures thereof and the salts thereof and the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids, pharmaceutical compositions containing these compounds, the use thereof and processes for the preparation thereof.
Public/Granted literature
- US20100234361A1 SELECTED CGRP-ANTAGONISTS, PROCESS FOR PREPARING THEM AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS Public/Granted day:2010-09-16
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