Invention Grant
- Patent Title: Selective antagonists of A2A adenosine receptors
- Patent Title (中): A2A腺苷受体的选择性拮抗剂
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Application No.: US11879133Application Date: 2007-07-16
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Publication No.: US07985754B2Publication Date: 2011-07-26
- Inventor: Anthony Beauglehole , Jayson M. Rieger , Robert D. Thompson
- Applicant: Anthony Beauglehole , Jayson M. Rieger , Robert D. Thompson
- Applicant Address: US MA Newton
- Assignee: Trovis Pharmaceuticals, LLC
- Current Assignee: Trovis Pharmaceuticals, LLC
- Current Assignee Address: US MA Newton
- Agency: McCarter & English, LLP
- Main IPC: C07D473/34
- IPC: C07D473/34 ; A61K31/52 ; A61P35/00 ; A61P25/16 ; A61P25/14
Abstract:
The present invention provides compounds of formulae Ia and Ib: wherein R1-5, Q, X, Y, Z, p, q, and r are as defined herein. The compounds are potent and selective antagonists of A2A adenosine receptors (ARs). The invention further includes pharmaceutical compositions containing these compounds and methods of using the same.
Public/Granted literature
- US20090118309A1 Selective antagonists of A2A adenosine receptors Public/Granted day:2009-05-07
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