Invention Grant
- Patent Title: Antimicrobial cathelicidin peptides
- Patent Title (中): 抗菌素肽肽
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Application No.: US12087228Application Date: 2006-12-29
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Publication No.: US07985832B2Publication Date: 2011-07-26
- Inventor: Tonatiuh Melgarejo , Frank Blecha , Yongming Sang , Maria Teresa Ortega
- Applicant: Tonatiuh Melgarejo , Frank Blecha , Yongming Sang , Maria Teresa Ortega
- Applicant Address: US KS Manhattan
- Assignee: Kansas State University Research Foundation
- Current Assignee: Kansas State University Research Foundation
- Current Assignee Address: US KS Manhattan
- Agency: Schwegman, Lundberg & Woessner, P.A.
- International Application: PCT/US2006/049637 WO 20061229
- International Announcement: WO2007/076162 WO 20070705
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/17 ; A61P31/00 ; A01N37/18 ; C07K14/00 ; C07K16/00 ; C07K17/00 ; C07K2/00 ; C07K4/00 ; C07K7/00 ; C07K5/00
Abstract:
The invention relates to antimicrobial cathelicidin polypeptides related to a 38 amino acid peptide having SEQ ID NO:4. The invention provides for polypeptides having broad spectrum antimicrobial activity, nucleic acids and expression vectors encoding such polypeptides, as well as host cells and methods of reducing survival of a microbe. In addition, the invention also provides compositions, as well as articles of manufacture, that comprise a broad spectrum antimicrobial polypeptide.
Public/Granted literature
- US20090221483A1 Antimicrobial Cathelicidin Peptides Public/Granted day:2009-09-03
Information query
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