Invention Grant
US07985837B2 Two component Bacillus lantibiotic and methods for producing and using the same
有权
双组分芽孢杆菌（Bacillus lantibiotic）及其生产和使用方法
- Patent Title: Two component Bacillus lantibiotic and methods for producing and using the same
- Patent Title (中): 双组分芽孢杆菌（Bacillus lantibiotic）及其生产和使用方法
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Application No.: US11931888Application Date: 2007-10-31
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Publication No.: US07985837B2Publication Date: 2011-07-26
- Inventor: Wilfred A. van der Donk , Lisa E. Cooper , Amanda L. McClerren
- Applicant: Wilfred A. van der Donk , Lisa E. Cooper , Amanda L. McClerren
- Applicant Address: US IL Urbana
- Assignee: The Board of Trustees of the University of Illinois
- Current Assignee: The Board of Trustees of the University of Illinois
- Current Assignee Address: US IL Urbana
- Agency: Licata & Tyrrell P.C.
- Main IPC: C07K1/00
- IPC: C07K1/00 ; C07K14/00 ; C07K17/00
Abstract:
The present invention relates to two-component lantibiotics isolated from Bacillus sp. Methods for producing said lantibiotics are provided, wherein dehydration and cyclization of the peptides is carried out by two substrate-specific modifying enzymes. Given the antimicrobial activity of the instant lantibiotics, methods for preventing or treating bacterial infections are also provided.
Public/Granted literature
- US20080242617A1 Two component bacillus lantibiotic and methods for producing and using the same Public/Granted day:2008-10-02
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