Regulation of endogenous gene expression in cells using zinc finger proteins

Invention Grant

US07985887B2 Regulation of endogenous gene expression in cells using zinc finger proteins 有权

Title translation: 使用锌指蛋白调节细胞内源性基因表达

Patent Title: Regulation of endogenous gene expression in cells using zinc finger proteins
Patent Title (中): 使用锌指蛋白调节细胞内源性基因表达
Application No.: US11505775

Application Date: 2006-08-17
Publication No.: US07985887B2

Publication Date: 2011-07-26
Inventor: George Norbert Cox, III , Casey Christopher Case , Stephen P. Eisenberg , Eric Edward Jarvis , Sharon Kaye Spratt
Applicant: George Norbert Cox, III , Casey Christopher Case , Stephen P. Eisenberg , Eric Edward Jarvis , Sharon Kaye Spratt
Applicant Address: US CA Richmond
Assignee: Sangamo BioSciences, Inc.
Current Assignee: Sangamo BioSciences, Inc.
Current Assignee Address: US CA Richmond
Agency: Robins & Pasternak LLP
Agent Dahna S. Pasternak
Main IPC: C12N15/09
IPC: C12N15/09 ; C12N15/31 ; C12N15/82 ; A01H5/00

Abstract:

The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.

Abstract(Chinese):

本发明提供了使用重组锌指蛋白调节内源细胞基因表达的方法。

Public/Granted literature

Information query

Espacenet

IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12N	微生物或酶；其组合物；繁殖、保藏或维持微生物；变异或遗传工程；培养基（微生物学的试验介质入C12Q1/00）。
C12N15/00	突变或遗传工程；遗传工程涉及的DNA或RNA，载体（如质粒）或其分离、制备或纯化；所使用的宿主（突变体或遗传工程制备的微生物本身入C12N1/00、C12N5/00、C12N7/00；新的植物入A01H；用组织培养技术再生植物入A01H4/00；新的动物入A01K67/00；含有插入活体细胞的遗传物质以治疗遗传疾病的药剂的应用，基因疗法入A61K48/00，一般肽入C07K）
C12N15/09	.DNA重组技术