A slide mechanism used in portable electronic device is described including a main plate, a slide plate, a parallelogrammically-shaped slider, and two guiders. The slider is attached to the slide plate. The guiders are attached to the main plate and configured for deformably guiding the slider to move therealong. The slider is positioned between the guiders. During the sliding process of the slide plate with respect to the main plate, two corners of the slider deform the guiders to slide the slide plate along the main plate.