Invention Grant
- Patent Title: Methods of treatment comprising administering an anti-sclerostin antibody
- Patent Title (中): 治疗方法包括施用抗硬化蛋白酶抗体
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Application No.: US12779438Application Date: 2010-05-13
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Publication No.: US07988970B2Publication Date: 2011-08-02
- Inventor: Andrew Ihor Korytko , David Matthew Marquis , Eric Michael Smith , Barbara Anne Swanson
- Applicant: Andrew Ihor Korytko , David Matthew Marquis , Eric Michael Smith , Barbara Anne Swanson
- Applicant Address: US IN Indianapolis
- Assignee: Eli Lilly and Company
- Current Assignee: Eli Lilly and Company
- Current Assignee Address: US IN Indianapolis
- Agent Alejandro Martinez; MaryAnn Wiskerchen
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395
Abstract:
Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.
Public/Granted literature
- US20100221263A1 Anti-Sclerostin Antibodies Public/Granted day:2010-09-02
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