Invention Grant
- Patent Title: Proofreading primer extension
- Patent Title (中): 校对引物扩展
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Application No.: US12538971Application Date: 2009-08-11
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Publication No.: US07989168B2Publication Date: 2011-08-02
- Inventor: Ellen Fiss , Thomas William Myers
- Applicant: Ellen Fiss , Thomas William Myers
- Applicant Address: US CA Pleasanton
- Assignee: Roche Molecular Systems, Inc.
- Current Assignee: Roche Molecular Systems, Inc.
- Current Assignee Address: US CA Pleasanton
- Agent Rhea Cyd Nersesiai
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The present invention provides for primer extension reactions, including polymerase chain reactions, in which a polymerase having 3′-5′ exonuclease activity edits a primer that is not fully complementary thereby allowing for amplification and detection of target nucleic acids that may have variability in their sequences.
Public/Granted literature
- US20100041053A1 PROOFREADING PRIMER EXTENSION Public/Granted day:2010-02-18
Information query
