Invention Grant
US07989172B2 Method of identifying a compound capable of modulating the Th2 polarization of CD4+ lymphocytes
有权
识别能调节CD4 +淋巴细胞Th2极化的化合物的方法
- Patent Title: Method of identifying a compound capable of modulating the Th2 polarization of CD4+ lymphocytes
- Patent Title (中): 识别能调节CD4 +淋巴细胞Th2极化的化合物的方法
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Application No.: US11662878Application Date: 2005-09-16
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Publication No.: US07989172B2Publication Date: 2011-08-02
- Inventor: Riikka Lund , Riitta Lahesmaa
- Applicant: Riikka Lund , Riitta Lahesmaa
- Applicant Address: FI Turun Yliopisto
- Assignee: Turun Yliopisto
- Current Assignee: Turun Yliopisto
- Current Assignee Address: FI Turun Yliopisto
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: FI20041204 20040916
- International Application: PCT/FI2005/050320 WO 20050916
- International Announcement: WO2006/030071 WO 20060323
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/567
Abstract:
The present invention provides methods utilizing novel target genes related to immune-mediated diseases, such as asthma, allergy and autoimmune diseases. The invention is based on a molecular level description of the polarization of CD4+ precursor cells (Thp) from which T helper cells are known to originate. Particularly, the present invention provides a method of identifying a compound capable of modulating the polarization of CD4+ lymphocytes. The invention is also related to a method for assessing the presence of, or disposition to, an immune-related disorder in a subject.
Public/Granted literature
- US20080168570A1 Methods for the Utilizaton of Novel Target Genes Related to Immune-Mediated Diseases Public/Granted day:2008-07-10
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