Invention Grant
- Patent Title: Mutant 6-phosphogluconate dehydrogenase
- Patent Title (中): 突变体6-磷酸葡萄糖酸脱氢酶
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Application No.: US12430592Application Date: 2009-04-27
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Publication No.: US07989191B2Publication Date: 2011-08-02
- Inventor: Masato Ikeda , Junko Ohnishi , Satoshi Mitsuhashi , Keiko Ochiai
- Applicant: Masato Ikeda , Junko Ohnishi , Satoshi Mitsuhashi , Keiko Ochiai
- Applicant Address: JP Tokyo
- Assignee: Kyowa Hakko Bio Co., Ltd.
- Current Assignee: Kyowa Hakko Bio Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Antonelli, Terry, Stout & Kraus, LLP.
- Priority: JP2001-368264 20011203
- Main IPC: C12N9/04
- IPC: C12N9/04 ; C12N1/20 ; C12N15/00 ; C12P13/04 ; C12P21/04 ; C12Q1/00 ; C12Q1/68 ; C07H21/04
Abstract:
The present invention relates to a polypeptide having a modified amino acid sequence of 6-phosphogluconate dehydrogenase (hereinafter abbreviated as GND) derived from a microorganism belonging to the genus Corynebacterium, said modification being substitution of the amino acid residue(s) at the position(s) corresponding to the 158th and/or the 361st amino acid(s) of the amino acid sequence shown in SEQ ID NO: 1, and having GND activity; DNA encoding the polypeptide; a recombinant DNA comprising the DNA; a transformant carrying the recombinant DNA; a microorganism carrying the DNA on the chromosome; and a process for producing a useful substance which comprises culturing the transformant or the microorganism in a medium.
Public/Granted literature
- US20100120088A1 MUTANT 6-PHOSPHOGLUCONATE DEHYDROGENASE Public/Granted day:2010-05-13
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