Invention Grant
- Patent Title: Therapeutic compounds
- Patent Title (中): 治疗化合物
-
Application No.: US12218425Application Date: 2008-07-15
-
Publication No.: US07989438B2Publication Date: 2011-08-02
- Inventor: Immacolata Conte , Joerg Habermann , Angela Mackay , Frank Narjes , Maria del Rosario Rico Ferreira , Ian Stansfield
- Applicant: Immacolata Conte , Joerg Habermann , Angela Mackay , Frank Narjes , Maria del Rosario Rico Ferreira , Ian Stansfield
- Applicant Address: IT Rome
- Assignee: Istituto di Ricerche di Biologia Molecolare P. Angeletti SpA
- Current Assignee: Istituto di Ricerche di Biologia Molecolare P. Angeletti SpA
- Current Assignee Address: IT Rome
- Agent Sheldon O. Heber; Julia M. Lake
- Priority: GBGB0713865.4 20070717; GBGB0724635.8 20071219
- Main IPC: C07D513/18
- IPC: C07D513/18 ; C07D513/22 ; C07D515/22 ; A61K31/4155 ; A61K31/454 ; A61K31/5517 ; A61P31/12
Abstract:
A class of macrocyclic compounds of formula (I), wherein R7, A, Ar, B, D, F, M, Q1, Q2, W, X, Y and Z are defined herein, that are useful as inhibitors of viral proteases, particularly the hepatitis C virus (HCV) NS3 protease, are provided. Also provided are processes for the synthesis and use of such macrocyclic compounds for treating or preventing HCV infection.
Public/Granted literature
- US20090048239A1 Therapeutic compounds Public/Granted day:2009-02-19
Information query
