Invention Grant
- Patent Title: Functionalized diarylisoxazoles inhibitors of ciclooxygenase
- Patent Title (中): 功能化二芳基恶唑抑制剂的环氧合酶
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Application No.: US12007571Application Date: 2008-01-11
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Publication No.: US07989450B2Publication Date: 2011-08-02
- Inventor: Antonio Scilimati , Paola Vitale , Leonardo Di Nunno , Paola Patrignani , Stefania Tacconelli , Marta Luciana Capone
- Applicant: Antonio Scilimati , Paola Vitale , Leonardo Di Nunno , Paola Patrignani , Stefania Tacconelli , Marta Luciana Capone
- Applicant Address: IT Bari IT Chieti
- Assignee: Universita' Degli Studi Di Bari,Universita' Degli Studi “G.D.'Annunzio”—Chieti
- Current Assignee: Universita' Degli Studi Di Bari,Universita' Degli Studi “G.D.'Annunzio”—Chieti
- Current Assignee Address: IT Bari IT Chieti
- Agency: Nixon & Vanderhye P.C.
- Main IPC: A61K31/42
- IPC: A61K31/42 ; A61K31/5355 ; C07D261/08 ; C07D413/06
Abstract:
Isoxazole derivatives, in particular diarylisoxazole derivatives inhibitors of cyclooxygenase (COX), in particular cyclooxygenase-1 (COX-1), their pharmaceutical compositions, the process for their preparation and their use for the chemoprevention and treatment of inflammatory syndromes and in the prevention and treatment of carcinomas, in particular intestinal, ovarian and cutaneous carcinomas, in the treatment of pain syndromes, in particular after surgery, and in the cardiovascular field as antithrombotics/vasoprotectives/cardioprotectives.
Public/Granted literature
- US20090181970A1 Functionalized diarylisoxazoles inhibitors of ciclooxygenase Public/Granted day:2009-07-16
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