Invention Grant
- Patent Title: Glucagon receptor antagonists, preparation and therapeutic uses
- Patent Title (中): 胰高血糖素受体拮抗剂，制剂和治疗用途
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Application No.: US11569273Application Date: 2005-05-13
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Publication No.: US07989457B2Publication Date: 2011-08-02
- Inventor: Mark Donald Chappell , Scott Eugene Conner , Isabel Cristina Gonzalez Valcarcel , Jason Eric Lamar , Jianke Li , Julie Sue Moyers , Rebecca Anne Owens , Allie Edward Tripp , Guoxin Zhu
- Applicant: Mark Donald Chappell , Scott Eugene Conner , Isabel Cristina Gonzalez Valcarcel , Jason Eric Lamar , Jianke Li , Julie Sue Moyers , Rebecca Anne Owens , Allie Edward Tripp , Guoxin Zhu
- Applicant Address: US IN Indianapolis
- Assignee: Eli Lilly and Company
- Current Assignee: Eli Lilly and Company
- Current Assignee Address: US IN Indianapolis
- Agent Dan L. Wood
- International Application: PCT/US2005/016637 WO 20050513
- International Announcement: WO2005/118542 WO 20051215
- Main IPC: C07D239/26
- IPC: C07D239/26 ; A61K31/505
Abstract:
The present invention discloses novel compounds of Formula (I), or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like.
Public/Granted literature
- US20080125468A1 Glucagon Receptor Antagonists, Preparation and Therapeutic Uses Public/Granted day:2008-05-29
Information query
