Invention Grant
- Patent Title: Pyrimidine derivatives as alk-5 inhibitors
- Patent Title (中): 嘧啶衍生物作为alk-5抑制剂
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Application No.: US12308232Application Date: 2007-07-12
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Publication No.: US07989458B2Publication Date: 2011-08-02
- Inventor: Catherine Leblanc , Maude Nadine Pierrette Pipet , Robin Alec Fairhurst , Claire Adcock , Robert Alexander Pulz , Duncan Shaw , Nikolaus Johannes Stiefl
- Applicant: Catherine Leblanc , Maude Nadine Pierrette Pipet , Robin Alec Fairhurst , Claire Adcock , Robert Alexander Pulz , Duncan Shaw , Nikolaus Johannes Stiefl
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Michael G. Smith; Philippe Mueller
- Priority: EP06117227 20060714; EP06119564 20060825
- International Application: PCT/EP2007/006192 WO 20070712
- International Announcement: WO2008/006583 WO 20080117
- Main IPC: A01N43/54
- IPC: A01N43/54 ; C07D239/02 ; C07D239/42 ; C07D401/00 ; C07D401/04 ; C07D403/00 ; C07D405/00 ; C07D409/00 ; C07D411/00 ; C07D413/00 ; C07D417/00 ; C07D419/00

Abstract:
Compounds of formula (I) in free or salt or solvate form, where T1, T2, Ra and Rb have the meanings as indicated in the specification, are useful for treating inflammatory or obstructive airways, pulmonary hypertension, pulmonary fibrosis, liver fibrosis, muscle diseases and systemic skeletal disorders. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Public/Granted literature
- US20090209539A1 Pyrimidine derivatives as alk-5 Inhibitors Public/Granted day:2009-08-20
Information query
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