Invention Grant
US07989462B2 4-arylamin-or-4-heteroarylamino-quinazolines and analogs as activators of caspases and inducers of apoptosis and the use thereof
失效
4-芳基氨基 - 或 - 4-杂芳基氨基 - 喹唑啉及其类似物作为胱天蛋白酶的活化剂和凋亡诱导剂及其用途
- Patent Title: 4-arylamin-or-4-heteroarylamino-quinazolines and analogs as activators of caspases and inducers of apoptosis and the use thereof
- Patent Title (中): 4-芳基氨基 - 或 - 4-杂芳基氨基 - 喹唑啉及其类似物作为胱天蛋白酶的活化剂和凋亡诱导剂及其用途
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Application No.: US11773303Application Date: 2007-07-03
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Publication No.: US07989462B2Publication Date: 2011-08-02
- Inventor: Sui Xiong Cai , Mark B. Anderson , Adam Willardsen , Nilantha Sudath Sirisoma , Hong Zhang , Kazuyuki Suzuki
- Applicant: Sui Xiong Cai , Mark B. Anderson , Adam Willardsen , Nilantha Sudath Sirisoma , Hong Zhang , Kazuyuki Suzuki
- Applicant Address: US UT Salt Lake City
- Assignee: Myrexis, Inc.
- Current Assignee: Myrexis, Inc.
- Current Assignee Address: US UT Salt Lake City
- Agency: Myrexis, IP Group
- Agent Kelly A. Echols; Herbert L. Ley, III
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/519 ; C07D401/00 ; C07D403/00 ; C07D413/00 ; C07D417/00 ; C07D419/00 ; C07D239/02
Abstract:
Disclosed are 4-arylamino-quinazolines and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
Public/Granted literature
- US20080004297A1 COMPOUNDS AND THERAPEUTICAL USE THEREOF Public/Granted day:2008-01-03
Information query
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