Invention Grant
- Patent Title: Macrocyclic inhibitors of hepatitis C virus
- Patent Title (中): 丙型肝炎病毒的大环抑制剂
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Application No.: US11995573Application Date: 2006-07-28
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Publication No.: US07989471B2Publication Date: 2011-08-02
- Inventor: Kenneth Alan Simmen , Herman Augustinus De Kock , Pierre Jean-Marie Bernard Raboisson , Sandrine Marie Helene Vendeville , Lili Hu , Wim Van De Vreken , David Craig McGowan , Abdellah Tahri , Dominique Louis Nestor Ghislain Surleraux
- Applicant: Kenneth Alan Simmen , Herman Augustinus De Kock , Pierre Jean-Marie Bernard Raboisson , Sandrine Marie Helene Vendeville , Lili Hu , Wim Van De Vreken , David Craig McGowan , Abdellah Tahri , Dominique Louis Nestor Ghislain Surleraux
- Applicant Address: IE County Cork
- Assignee: Tibotec Pharmaceuticals Ltd.
- Current Assignee: Tibotec Pharmaceuticals Ltd.
- Current Assignee Address: IE County Cork
- Priority: EP05107067 20050729; EP05107413 20050811
- International Application: PCT/EP2006/064813 WO 20060728
- International Announcement: WO2007/014919 WO 20070208
- Main IPC: A61K31/47
- IPC: A61K31/47 ; C07D245/00

Abstract:
Inhibitors of HCV of formula (I) and the N-oxides, salts, and stereochemically isomeric forms thereof, wherein the terms R1, L, R2, R3, R4, and n have specific definitions; pharmaceutical compositions containing compounds of formula (I), and processes for preparing compounds of formula (I). Bioavailable combinations of the inhibitors of HCV of formula (I) with ritonavir are also provided.
Public/Granted literature
- US20100240698A1 MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS Public/Granted day:2010-09-23
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