Invention Grant
- Patent Title: Smooth muscle peristole inhibitor
- Patent Title (中): 平滑肌肉组织抑制剂
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Application No.: US10515129Application Date: 2003-05-20
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Publication No.: US07989503B2Publication Date: 2011-08-02
- Inventor: Tomonori Hamawaki
- Applicant: Tomonori Hamawaki
- Applicant Address: JP Tokyo
- Assignee: Nihon Pharmaceutical Co., Ltd.
- Current Assignee: Nihon Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2002-147372 20020522; JP2002-379522 20021227
- International Application: PCT/JP03/06304 WO 20030520
- International Announcement: WO03/097026 WO 20031127
- Main IPC: A61K31/045
- IPC: A61K31/045

Abstract:
An emulsion comprising L-Menthol, a fat or oil and a surfactant wherein oil particles have an average diameter of 100 nm or less inhibits a content reduction attributed to, for example, evaporation of L-menthol, enhances a light transmission through liquid and is stable despite long-term storage. Thus, the emulsion can be appropriately used in the temporary inhibition of contraction of gastrointestinal tract for, for example, observation of gastrointestinal tract by an endoscope. This emulsion can be obtained by heating an oil-in-water type emulsion comprising L-menthol, a fat or oil and a surfactant at 60° C. or higher.
Public/Granted literature
- US20050239905A1 Smooth muscle peristole inhibitor Public/Granted day:2005-10-27
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