Invention Grant
- Patent Title: Compstatin analogs with improved activity
- Patent Title (中): 补充剂类似物具有改善的活性
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Application No.: US10528496Application Date: 2003-09-22
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Publication No.: US07989589B2Publication Date: 2011-08-02
- Inventor: John D. Lambris
- Applicant: John D. Lambris
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees Of The University Of Pennsylvania
- Current Assignee: The Trustees Of The University Of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Potter Anderson & Corroon LLP
- International Application: PCT/US03/29653 WO 20030922
- International Announcement: WO2004/026328 WO 20040401
- Main IPC: A61K38/10
- IPC: A61K38/10 ; A61K38/00 ; A61K51/00
Abstract:
Compounds comprising peptides and peptidomimetics capable of binding the C3 protein and inhibiting complement activation are disclosed. These compounds display improved complement activation-inhibitory activity as compared with currently available compounds. Isolated nucleic acid molecules encoding the peptides are also disclosed.
Public/Granted literature
- US20100222550A1 Compstatin analogs with improved activity Public/Granted day:2010-09-02
Information query
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