Invention Grant
- Patent Title: Process for the purification of gabapentin
- Patent Title (中): 加巴喷丁的纯化方法
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Application No.: US11722056Application Date: 2005-12-15
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Publication No.: US07989658B2Publication Date: 2011-08-02
- Inventor: Roberto Giovanetti , Andrea Nicoli , Livius Cotarca
- Applicant: Roberto Giovanetti , Andrea Nicoli , Livius Cotarca
- Applicant Address: IT Bresso
- Assignee: ZaCh System S.p.A.
- Current Assignee: ZaCh System S.p.A.
- Current Assignee Address: IT Bresso
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: ITMI2004A2418 20041217
- International Application: PCT/EP2005/056817 WO 20051215
- International Announcement: WO2006/064041 WO 20060622
- Main IPC: C07C227/40
- IPC: C07C227/40 ; C07C229/28
Abstract:
The present invention relates to a process for the purification of gabapentin. The process relates to the addition of hydrochloric acid to an aqueous solution or suspension of gabapentin, before, during or after the concentration step of that solution, and the subsequent slurry of the gabapentin by the addition of an alcoholic solvent. The so obtained gabapentin has an high purity degree and, in particular, is characterized by a low content of lactam.
Public/Granted literature
- US20090292138A1 PROCESS FOR THE PURIFICATION OF GABAPENTIN Public/Granted day:2009-11-26
Information query
