Systems and methods for monitoring, making, managing and controlling telephone communications with a computer call assistant with an integrated voice/data communications system are disclosed. A call assistant computer application preferably runs on a personal computer (“PC”) coupled to the integrated system over a packet bus. The call assistant exchanges control and/or status packets with the integrated system preferably over a packet bus. The call assistant enables the user to make, receive and control telephone calls, monitor the status of the user's extension, voice mail, etc., and preferably operates with integrated systems capable of transmitting and receiving voice and data in multiple modes. In preferred embodiments, the computer call assistant operates with systems that are capable of multiple native mode voice and data transmissions and receptions with a communications system having a multi-bus structure, including, for example, a time division multiplexed (“TDM”) bus, a packet bus, and a control bus, and multi-protocol framing engines, preferably including subsystem functions such as PBX, voice mail, file server, web server, communications server, telephony server, LAN hub and data router.