An apparatus and method for outputting audio in a portable terminal are provided. The apparatus includes a communication module for transmitting/receiving a call connection request and speech signals during a call connection service; an audio processor connected to at least one audio output device, for controlling the output audio data/speech signals through the audio output device, which is a first audio output device, and checking whether another audio output device is connected; and a controller for checking at the audio processor whether there is another audio device, which is a second audio output device, for outputting the speech signals received while outputting the audio data of an application service through the first audio output device, and when there is the second audio output device, for controlling the output of the speech signals through the second audio output device.