Connection architectures, methods, systems and computer readable media are described. In one exemplary embodiment, a computer readable medium comprises a first software component which is configured to interface, through first software based messages, with synchronization software components during a structured data synchronization process between a host and a device and which is configured to interface, through second software based messages, with a plurality of different stream handlers for a corresponding plurality of physical interfaces. Systems, methods, architectures and other computer readable media are also described.