A urine collection and disposal system and method applies subatmospheric pressure to a receptacle open to atmospheric pressure which has a urine outlet in fluid communication with a source of subatmospheric pressure. The receptacle receives urine in the receptacle from a urine donor and removes the urine from the receptacle, transporting the removed urine to a reservoir under the force of a pressure differential between atmospheric pressure at the receptacle and subatmospheric pressure at the reservoir. The reservoir urine is discharged at atmospheric pressure, for disposal, from the reservoir while maintaining the reservoir at subatmospheric pressure. A plurality of the receptacles allows simultaneously providing urine to the reservoir from more than one of the receptacles. Sanitizing fluid may be supplied intermediate the receptacle and the reservoir for transport to the reservoir under the force of the pressure differential between atmospheric and subatmospheric.