A disposable air filter and grill assembly is disclosed which eliminates the undesirable need of cleaning conventional air filter grills. The assembly includes a frame which can be mounted within a grid of a drop ceiling or other opening loading to a space to be heated and/or cooled. The frame includes a plurality of clips to removably secure a disposable filter unit therein. The disposable filter unit includes an outer shell within which filter media is positioned. After the unit has been used a sufficiently long period of time and needs to changed, the clips can be disengaged, the disposable filter unit can be removed, and a new unit can be installed. Accordingly, as opposed to cleaning existing grills which often result in a less than properly maintained facility or an aesthetically undesirable facility, the apparatus disclosed herein provides an aesthetically pleasing, functional, and easily maintained system.