Invention Grant
- Patent Title: HPRP4s modifiers of the p53 pathway and methods of use
- Patent Title (中): HPRP4s p53途径的修饰和使用方法
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Application No.: US11627831Application Date: 2007-01-26
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Publication No.: US07993829B2Publication Date: 2011-08-09
- Inventor: Lori Friedman , Gregory D. Plowman , Tak Hung , Helen Francis-Lang , Danix Li , Roel P. Funke , Michael Costa
- Applicant: Lori Friedman , Gregory D. Plowman , Tak Hung , Helen Francis-Lang , Danix Li , Roel P. Funke , Michael Costa
- Applicant Address: US CA South San Francisco
- Assignee: Exelixis Inc.
- Current Assignee: Exelixis Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
Human hPRP4 genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of hPRP4 are provided.
Public/Granted literature
- US20070160539A1 HPRP4s Modifiers of the p53 Pathway and Methods of Use Public/Granted day:2007-07-12
Information query
