Invention Grant
- Patent Title: Assay for identifying antibody producing cells
- Patent Title (中): 用于鉴定抗体产生细胞的测定
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Application No.: US10537309Application Date: 2003-12-01
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Publication No.: US07993864B2Publication Date: 2011-08-09
- Inventor: Derek Thomas Brown , Lisa Butler , Karen Dorothy Cromie , Meryn Ruth Griffiths , Alastair David Griffiths Lawson , Daniel John Lightwood
- Applicant: Derek Thomas Brown , Lisa Butler , Karen Dorothy Cromie , Meryn Ruth Griffiths , Alastair David Griffiths Lawson , Daniel John Lightwood
- Applicant Address: BE Brussels
- Assignee: UCB Pharma S.A.
- Current Assignee: UCB Pharma S.A.
- Current Assignee Address: BE Brussels
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Priority: GB0228188.9 20021203; GB0319587.2 20030820
- International Application: PCT/GB03/05254 WO 20031201
- International Announcement: WO2004/051268 WO 20040617
- Main IPC: C12P21/08
- IPC: C12P21/08 ; G01N33/53
Abstract:
The present invention provides a homogeneous assay for identifying an antibody producing cell producing an antibody which binds to a selected antigen comprising: a) providing a population of antibody producing cells; b) incubating said population of antibody producing cells with a selected antigen and a labeled anti-antibody antibody, wherein said anti-antibody antibody is capable of distinguishing cells producing an antibody which binds to the selected antigen from those cells which do not; and c) identifying an antibody producing cell capable of producing an antibody which binds to the selected antigen.
Public/Granted literature
- US20060148012A1 Assay for identifying antibody producing cells Public/Granted day:2006-07-06
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