Invention Grant
- Patent Title: Precircle probe nucleic acid amplification methods
- Patent Title (中): 前置探针核酸扩增方法
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Application No.: US12709319Application Date: 2010-02-19
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Publication No.: US07993880B2Publication Date: 2011-08-09
- Inventor: Thomas D. Willis , Paul Hardenbol , Maneesh Jain , Viktor Stolc , Mostafa Ronaghi , Ronald W. Davis
- Applicant: Thomas D. Willis , Paul Hardenbol , Maneesh Jain , Viktor Stolc , Mostafa Ronaghi , Ronald W. Davis
- Applicant Address: US CA Stanford
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Stanford
- Agency: Morse, Barnes-Brown & Pendleton, PC
- Agent Lisa M. Treannie, Esq.
- Main IPC: C12P19/34
- IPC: C12P19/34 ; C07H21/02 ; C07H21/04 ; C12Q1/68
Abstract:
The invention is directed to novel methods of multiplexing nucleic acid reactions, including amplification, detection and genotyping. The invention relies on the use of precircle probes that are circularized in the presence of the corresponding target nucleic acids, cleaved, and then amplified.
Public/Granted literature
- US20100330619A1 DIRECT MULTIPLEX CHARACTERIZATION OF GENOMIC DNA Public/Granted day:2010-12-30
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