Invention Grant
US07993904B2 Process for the preparation of optically active 5-substituted 2-oxazolidinones from racemic epoxides and cyanate employing a halohydrin dehalogenase
有权
使用卤代醇脱卤酶从外消旋环氧化物和氰酸盐制备光学活性的5-取代的2-恶唑烷酮的方法
- Patent Title: Process for the preparation of optically active 5-substituted 2-oxazolidinones from racemic epoxides and cyanate employing a halohydrin dehalogenase
- Patent Title (中): 使用卤代醇脱卤酶从外消旋环氧化物和氰酸盐制备光学活性的5-取代的2-恶唑烷酮的方法
-
Application No.: US12279786Application Date: 2007-02-28
-
Publication No.: US07993904B2Publication Date: 2011-08-09
- Inventor: Bernhard Hauer , Dirk Barend Janssen , Maja Majeric Elenkov
- Applicant: Bernhard Hauer , Dirk Barend Janssen , Maja Majeric Elenkov
- Applicant Address: DE Ludwigshafen
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE Ludwigshafen
- Agency: Conolly Bove Lodge & Hutz LLP
- Priority: EP06110638 20060303
- International Application: PCT/EP2007/051861 WO 20070228
- International Announcement: WO2007/099107 WO 20070907
- Main IPC: C12P17/14
- IPC: C12P17/14 ; C12P41/00
Abstract:
A process for the production of an optically enriched oxazolidinone of the formula (2a) or (2b), by reacting an epoxide of the formula (1) with cyanate in the presence of halo-hydrin dehalogenase.
Public/Granted literature
Information query
