Invention Grant
US07994137B2 Small peptides and methods for inhibiting the infiltration of eosinophils into airways
失效
用于抑制嗜酸性粒细胞浸润到气道中的小肽和方法
- Patent Title: Small peptides and methods for inhibiting the infiltration of eosinophils into airways
- Patent Title (中): 用于抑制嗜酸性粒细胞浸润到气道中的小肽和方法
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Application No.: US11942371Application Date: 2007-11-19
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Publication No.: US07994137B2Publication Date: 2011-08-09
- Inventor: John C. Houck , James Clagett
- Applicant: John C. Houck , Mary MacDonald, legal representative , James Clagett
- Applicant Address: US WY Big Horn
- Assignee: Mowycal Lending, LLC
- Current Assignee: Mowycal Lending, LLC
- Current Assignee Address: US WY Big Horn
- Agency: Lathrop & Gage LLP
- Main IPC: A61K38/07
- IPC: A61K38/07 ; C07K5/00

Abstract:
Methods for treating cutaneous inflammation, are described. Also described is a method for inhibiting the mucous release into airways of a patient, methods for blocking IgE activation and for stabilizing the cell membrane of lymphocytes, mast cells, basophils, macrophages, monocytes, eosinophils, neutrophils, and the like, thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.
Public/Granted literature
- US20080214478A1 Small Peptides And Methods For Inhibiting The Infiltration Of Eosinophils Into Airways Public/Granted day:2008-09-04
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