Invention Grant
- Patent Title: Process for the preparation of a composition of genetically modified hematopoietic progenitor cells
- Patent Title (中): 用于制备遗传修饰的造血祖细胞的组合物的方法
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Application No.: US10483347Application Date: 2002-07-10
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Publication No.: US07994144B2Publication Date: 2011-08-09
- Inventor: Geoffrey P. Symonds , Rafael Amado , Lun-Quan Sun , Janet Macpherson , Greg Fanning , Wayne Gerlach
- Applicant: Geoffrey P. Symonds , Rafael Amado , Lun-Quan Sun , Janet Macpherson , Greg Fanning , Wayne Gerlach
- Applicant Address: AU Eveleigh
- Assignee: Johnson & Johnson Research Pty, Limited
- Current Assignee: Johnson & Johnson Research Pty, Limited
- Current Assignee Address: AU Eveleigh
- Agency: Cooper & Dunham LLP
- Agent John P. White
- International Application: PCT/US02/21907 WO 20020710
- International Announcement: WO03/006691 WO 20030123
- Main IPC: A01N43/04
- IPC: A01N43/04 ; C12N5/08 ; C12N15/63 ; C12Q1/68 ; C07H21/04

Abstract:
Described are compositions and methods relating to gene therapy, particularly as applied to hematopoietic progenitor (HP) cells, to transduced cells and methods of obtaining them, and to methods of using them to provide prolonged engraftment of modified hematopoietic cells in human subjects. The invention particularly relates to ex vivo gene therapy of HP cells for treatment or prevention of HIV infection.
Public/Granted literature
- US20050063958A1 Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells Public/Granted day:2005-03-24
Information query
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