Invention Grant
- Patent Title: Dihydropyridine derivatives
- Patent Title (中): 二氢吡啶衍生物
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Application No.: US11912719Application Date: 2005-05-04
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Publication No.: US07994189B2Publication Date: 2011-08-09
- Inventor: Nicole Corine Renee Van Straten , Gerritdina Geziena Gerritsma , Lars Anders Van Der Veen
- Applicant: Nicole Corine Renee Van Straten , Gerritdina Geziena Gerritsma , Lars Anders Van Der Veen
- Applicant Address: NL Oss
- Assignee: N.V. Organon
- Current Assignee: N.V. Organon
- Current Assignee Address: NL Oss
- Agent Patricia A. Shatynski; Valerie J. Camara
- International Application: PCT/EP2005/052042 WO 20050504
- International Announcement: WO2006/117023 WO 20061109
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A61K31/47
Abstract:
The present invention relates to dihydropyridine derivatives having general formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 is (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl, phenyl, (1-5C)heteroaryl R2, R3 are independently (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl, (1-4C)alkoxy, (24C)alkenyloxy, (2-4C)alkynyloxy, halogen X is SO2, CH2, C(O) or X is absent R4 is (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl, (3-6C)cycloalkyl, (3-6C)cycloalkenyl, (3-6C)cycloalkyl(1-4C)alkyl, (2-6C)heterocycloalkyl, (2-6C)heterocycloalkyl(14C)alkyl, (6-1 OC)aryl, (6-10C)aryl(1-4C)alkyl, (1-9C)heteroaryl or (1-9C)heteroaryl(14C)alkyl. The compounds are useful for the treatment of fertility disorders.
Public/Granted literature
- US20090215773A1 DIHYDROPYRIDINE DERIVATIVES Public/Granted day:2009-08-27
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